There is a huge difference in brass base wall thickness between the 44 and the 45 Colt, and no, I do not mean the antique folded rim 45 colt, I mean even modern 45 Colt brass. Brass is a gasket, thats it, just like the head gasket on car, or think of it as a pressure valve, once the "valve" leaks, it matters not what the strength of the tank the valve is in.
Most modern rifles steel is in the low three digit range of holding PSI, but the BRASS starts to fail at around 75,OOO PSI. While a combination of factors apply, the brass has as much to do with it as the action strength.
but if a guy just sticks with the book loads, and every modern one I know of discusses the load limits in the modern lever guns like the 1894, one will have no issues, assuming they followed all the other common sense rules in handloading.
Like guys wanting to hot load the Smith 25-5 in 45 colt, hey first, the put the cylinder lock notches right over the chamber, while the 29 Smith in 44 mag are between the chambers, same with the Blackhawk and Super Blackhawk, a huge difference in cylinder design. If a guy wants to shoot 44 mag loads, they should get a 44 mag, or if they want a hot 45 bullet, get a 454 or what ever other variation.
but if guys want to swim in deep water, dont be surprised if its over the head. Same with hot loading guns. Dont blame the gun maker, if the gun comes apart when loading "off the reservation".:biggrin:
Like the last post hints, a good safe load even if at the high end, but still in the book range, will kill most anything a guy should be shooting with a handgun. Can never figure it out, a guy will shoot a big hairy dangerous critter with a 44 mag, just cause it say "mag" on the ammo box, yet they have kittens when some guy might walk up there with a 30 30, with down range energy etc, being real close to the same.