Having shot my Guide Gun 45-70 through the many years I have had it and mostly with cast bullets in 350 gr. or 405 grain,it has become my favorite go to rifle for deer hunting here in Ohio. It's short and sweet, easy to carry, perfect for the tree stand hunting and is way more accurate then my two 44 magnum rifles which is a Henry Big Boy Steel and a Ruger 77/44.My Guide Gun isn't particular with most any loads I develop for it. My wife and I both bought 45-70 Guide Guns, mainly to use for hunting Black Bear in Canada but my rifle has proven the virtues of the old 45-70 cartridge. Oh, I have had guys tell me that it is more gun then needed for deer but then when I ask them why they hunted many years with 12 ga. slug guns or 50 and 54 caliber Muzzle loaders which can throw bigger projectiles then even my 45-70,they didn't have an answer for it. Reminds me of some that speak before they think when they make posts cutting down a caliber or cartridge or long barrel versus short barrel. My Guide Gun is good to 150 yards, my 44 magnums are not and I wouldn't even try that with a 45 Colt.