All the other voters here don't know cars well enough for their votes to mean anything ;D
The 39A is the Cadillac of .22s. You can
spend more on a rifle, but you probably won't enjoy owning and using another rifle any more than this one.
The Anschutz is the Porsche of .22s, but worthless to me as they don't make lefty models. German performance for a price that is out of reach for many.
The CZ 452 (I own one, haven't ever seen a 455 but I bet they're similarly good) is the Corvette of .22s, and available either left or right handed. Sleek high performance that anyone can afford.
The Blaser is the Rolls-Royce of .22s for obvious reasons. The ultimate in luxury, very uncommon, breathtakingly expensive, powerful (lightning fast action and modular), etc., etc.
Any one of these would serve its owner supremely well as an only rimfire rifle.