I've recently been doing a lot of shooting with Bullseye and 148-160 grain cast wadcutters in the 35 Remington cartridge. Just under 5 grains (4.7-4.8 grains depending upon bullet) gives around 1050 fps, bullets are stabilized to at least fifty yards or more, accuracy is good, and report is mild.
The case necks are a little sooty because pressure is low, but a useful load it is for cheap practice, small game or pests. I don't find it necessary to use fillers as long as you're reasonably certain to keep the powder somewhere around the back or middle of the case. In other words, don't let it bunch up around the bullet before firing and you'll be fine. Titegroup is noted for being especially position insensitive as long as you're being halfway reasonable with the powder charge.
Good results may be had with no filler.