I get around 2800 fps with my H4350/58gr out of my 24" CDL. I bought some H414 today, along with a box of the Hornady 165 GMX. I am a die hard loyal Barnes fan, but have to give these a whirl, I think I will try and work up to 59-60 gr, depends on the rifle/chrono.
I have had one "fast" 22" barreled '06, gave very high speeds for what was routine in other rifles. I like to work up to full potential of the case/bullet combo, usually until either accuracy goes south or chrono shows diminishing returns. I would rather have accuracy over speed, especially with a good bullet design, it just isn't needed for my uses. My 200 Partition reaches 2650, the 240 Woodleigh gets an honest 2400+. I didn't clock the Nosler 125's but it is humming, and scary accurate. BTW, that NBT 125 is a heck of a deer bullet, really puts the stink on 'em, and almost turns a coyote inside out! It will open up a big rockchuck like a $4 cheap suitcase, "wide open"! ha.