I'm not at all tempted to interchange Large Rifle with Large Pistol since I only stock 3 types of primers: Large Rifle, Small Pistol, and Small Pistol Magnum. And I'm still working on that same 1000 round brick of Federal small pistol magnum primers I bought years ago, I only use them when I'm loading H110 in .357 Mag, I've still got half the brick left.
If it got really bad and I just couldn't get any primers at all (which was almost the case a couple of years ago, thankfully I had a pretty good supply on hand to see me through), then that's another thing. But I haven't gotten to that point yet.
My new project is to see if the (much cheaper, online) Ruskie Wolf primers are any good. I just got a brick of Wolf Large Rifle and a brick of Small Pistol primers. Reports I've gotten are that they are a wee bit thinner and that you have to take that into account when seating them, and that they don't do all that well with striker fired guns. Neither of which should be a problem for me. I've got trial batches brewed up, ready for the next range trip. If they pan out, I'm ordering up a bunch of them, I'm not going to be caught shy of primers. I'm going to head off that beast by having a hefty supply on hand, even if they are Ruskie primers (assuming they pan out).