I find IMR 4198 to be an very consistent powder, some of my loads with the 405 grain cast only varied 10 or 12 fps.
27.2 grs. of it was the sweet spot in my 18.5" Cowboy, very accurate and pleasant to shoot, and gave 1150 fps. 30 grains was also nice, and gave 1270 fps.
I also use Starline brass, with W-W primers. Starline brass, as mentioned above, is thicker than Winchester and has quite a bit less case capacity, so beware, if nearing max loads that were tested in the manual with W-W or other thinner brass.
H4198 is just as consistent as IMR 4198, but is easier to flow through a measure. Any IMR stick powder crunches it's way though your powder measure. I still have a pound of IMR, but once it'd gone I'll be switching to the H version. ( And have to work up new loads ).
IMR 4198 is right next to H4198 on the burning chart, it is the faster one. I wouldn't worry at all substituting the slower H4198 for IMR data.
Using the faster IMR when the manual used H, maybe just reduce it slightly.
I don't see why you can't stick with Unique for loads in the 1300 fps. range. I could not find Unique for sale a few years ago ( or any pistol powder ) but did get an 8 lb. jug of Hodgdon Universal. ( Not Clays Universal, that is a much faster burning shotgun powder. I know, kind of confusing on Hodgdon's part, as my jug says "Universal, with Clays Technology". I noticed new jugs of Universal have that removed. Load Clays Universal at Universal charges and it would be a stiff load indeed. Clays is #8 on the powder burn rate chart, Universal is #30. Unique is #26).
It has a very similar burning rate to Unique but a bit slower, but much cleaner burning in my experience.
I found the best accuracy at 12.0 grains,it gave 1100 fps. But 14 grains was also good at 1240 fps. 15 grains should be doable. and might get you close to 1300 fps. Universal is a VERY consistent powder, most of my 5 shot strings only varied 4 or 5 fps.
Only down side to a faster powder like Unique or Universal is the chance of a double charge, inspect rows of cases carefully before seating bullets.
Upside is you'll get the same accuracy, and the same 1300 fps velocity you're looking for, and be using half as much powder to do it.