I have loved the .243 since the day a guy handed me his pre62 model 70 w/4x Leupold and a BAG of loads.
This was back in the 50s, and as a kid, I always saw cartridges in 20 for centerfire, 25 for shotgun and 50 for .22s, but to hand a kid a bag of cartridges and tell him to have at it was awesome.
We lived 7 miles from the next place, so I just set down on the back porch and started shooting at the rocks on the hills above the house.
The old 32 Special, was bang, wait a second and maybe smack. With the 243 it was put the dot of the scope on a rock, pull the trigger and smack the dust flew. WOW!!!!!!!!!! Been a love afair ever since.
It was also one of my first things to reload for, early to mid 60s.
You mention 4895, and as good as a powder as it is, if you'll check the load manuels you will find that slower powders give better results all the way down to the 75gr bullets or below.
The faster powders come into their own with bullets like the 55 & 60gr weights.