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I run them at 1500-1550 in my guide gun. Have not run that load over the chrony in My CB. This load is about .75 gr under uncomfortable.
 
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999 fps does it for me. Penetrates through 14 1 gal milk jugs filled with water and a 5 shot group @ 50 yds into 3/16". Course my longest shot would be 70 yds, but it does the job.
 

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Years ago I took a mule deer doe with the 405, handloaded to about 1650 fps. Bullet performance was very good. Because of intervening tall grass, I had only a "high shoulder shot" at about 70 yards, so I took it. Broke the spine and went through both shoulder blades. Bullet is somewhere in the hillside beyond the deer.
 

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That's a very good bullet and in a good rifle it's very accurate as well.

I load mine to 1,300 fps to mimic the classic infantry load in a Trapdoor rifle, While I don't shoot them in my original Trapdoors, I shoot a lot of them in my Marlin 1895 Limited. Solid 1 1/2 to 2 MOA performance out to 200 yards with a Lyman Model 66 aperture sight and a blade front sight.
821308
 

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I load my Rem 405's over 35gr H4198. Haven't measured them on my Chrony but it's probably in the 1500 fps range.
 
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