Not sure where you live, but in my part of the country, any one of those shots would drop any whitetail dead in his tracks with proper placement. Although I love my leverguns, my go-to deer rifle is my bolt-action .270 with Zeiss scope. Hope to use my 1894 .44 Magnum next deer season in the thick stuff, but certainly not over a field at more than 75 yards with a peep sight!
If you're trying to get a better grouping (target shooting, whatever) that's another story...I can't speak as to reloading, I just use Hornady 130-gr. red ballistic tips off the shelf.
Good luck with whatever you need to group at 100 yds!