My best friend is a prairie dog shooter and regularly shoots them at 600 yards which I think is great!
He also hunts deer with the same rifle, we have a little back and forth about him hunting deer with an inferior caliber. He is a crack shot! If you use a 22 caliber rifle it’s all about shot placement. I just think there are better options.
Also saw him shoot an antelope buck at 450 yards that was DRT!