I see it as more of a "too much load" vs. "too much gun" My philosophy has always been heavier and slower ruins less meat than heavier/faster, lighter/faster. It seems to me that if I produce a load where the gozinta is caliber and the gozouta is ~4X caliber...that's the limit....example...with my 45-70, I want no more than a 2" exit hole. My 30-06 I want no more than a 1.5" exit hole. The larger the hole....the more meat you've removed/damage. The deer is just as dead...true....but what is your goal? Mine is to keep as much freezer meat as possible.
Yes...I at one time had my loads cranked up where I had 4-5" exit holes from my 30-06....but it left me with about 10-15 lbs of unusable bloodshot meat....so what was the point?
This is all to say...I never shoot more than 150 yards...its a personal limit I set on myself. Sometimes a lighter/faster bullet is required....especially when reaching out 200+ yards. But again this is a variable where I won't put myself in that situation. So...for me...heavier/slower is the way to go.