Speaking of rifles & bullets for white tail deer, I think there is a lot of over thinking. I have killed a deer with 25/20 and 32/20 with a cast bullet. I sat on a stump and waited for a good shot. I killed the deer but could have done it with a 22 under same conditions. I would not carry either of these rifles the way I normally hunt, which is sneaking around thick stuff and shooting deer on the jump. I wouldn't use a 22cf rifle for this either. If you are stump hunting it really makes no difference what you use if you put a decent shot on the deer.
When I'm going to areas of open ground I use a BA / scope. From 243 up. If magnum I used a bullet and velocity that won't blow the deer in half. The longest shot I've made on a deer while hunting is 250yds with a 308/6x scope. I wouldn't have tried that shot but the deer was stationary and I was able to take up a rest. I have shot damage permit deer shooting from a rest out to 300yds with 243 and 270 but that is shooting, not hunting. Shooting from bags at stationary deer is like shooting groundhogs. One guy that shoots permits uses a 220swift with 55gr FMJ / 16x scope. He only takes head shots and he doesn't loose any.
Here in Ohio the new rifle season has all the young guys buying Marlin 1895 guide guns. Most deer are shot at under 100yds and most hunters are shooting from stands. They all think they need some gimmick bullet to kill a average 150lb deer. I have never had trouble killing deer with any caliber rifle. I have used solid cast and expanding bullets and the only bad experience I've had was with 30/06 Winchester silver tips. When I was a teenager I shot a deer to pieces with them. They were going through like FMJs and my hits weren't good except first that hit high in the lungs.
I think the rifle you pick should be geared more by cover and method of hunting that by caliber. Depending on these almost any rifle will kill a deer. They ain't Cape Buffalo.