I am not a fan of the plastic glowing sights, but too each his own. Far as taking the old ones out, drive them out too the right, as the muzzle is pointing away from you, and drive them in too the left. Not all newer guns even use a tapered dovetail, but its a good rule to follow.
Depending on the factors, they may be a tighter than a bulls butt in fly time, and a good vice with fiber or hard wood jaws and brass drift will be needed, or they may near fall out. Only way to tell will be to try.