Yes, I've chronographed for just that effect, deliberately, many times.
The extreme spreads that result are, as you'd expect, based upon just how full the case is of powder, as well as the bullet used. Standard pressure is more position sensitive than Plus P loadings, and less position sensitive than lower velocity loadings. Again, just as you'd expect. High velocity 185's with their shallower seating are more position sensitive than high velocity 230's with their deeper seating, even given that the powder charges with the 185's are larger. A function of the variability of the shot start pressure of the lighter bullet, and the extra powder doesn't make up for the shallower seating.
If standard pressure is taken to mean 230's at ~830 fps, and 200's at 900+ fps, extreme spreads (not averages, but rather highs and lows) will generally be 50 fps or less using cases of the same make. If the bullet seats shallowly, like some of the once popular 155's, and loads are more moderate, extreme spreads may approach 100 fps. This is not unusual with the best of powders, and Titegroup, while being fairly position insensitive, is really not more so than the more bulky Bullseye and Unique.
If you want bulkiness at low charge weight with relative position insensitivity, you'd tend more to Red Dot.
I say "relative" because there's no powder I've tested that is completely insensitive to position, even in the stubby ACP case.
A powder that has proven curiously position sensitive when exposed to this testing is Universal. I would appreciate if you could confirm this in your own testing.
If you want figures, I'd be happy to post them. I've done this with a number of other powders as well.