Tim, I love experimenting with new powders, but if you're already getting good results with Varget, you might as well stick with it. I get great accuracy (though not the highest velocity) with Varget in my 223's, both bolt-action and semi-auto. I don't have a .243, but I bet it would serve you well there, too. One thing though.........I see maximum load data for the 223 showing as much as 27.5 grains of Varget with a given bullet. Try as I might, I've never been able to get more than 26.5 or so into the case before it overflows, so I just fill the case to the base of the bullet and go shooting. I like high load density, but I think compressed charges are an unnecessary hassle. YMMV.
BTW, if anyone tries that Pro Varmint powder with the 130-grain bullet, I'd love to know what kind of velocity you're getting. That bullets shoots really well in my 1964 RC, and Alliant claims a top velocity of 2582 fps from a 24-inch tube. I may have to try that powder myself, their new 2000-MR is my new favorite .308 powder, I just bought three more pounds of it, and ordered another eight pounds from Graf's. Yes, In my rifle, it's THAT good. On a good day, it will do this well at 200 yards.