We have 2 - .243 win rifles as well as a 25-06. My girlfriend used to use the .243 for deer but I bought her the 25-06 to give her "more reach". The .243 is probably the cheapest ammo wise and is certainly enough for whitetail - but - I rate it out to around 150yds for use on deer. That's just me - with accurate placement I'm sure you can extent that. The 25-06 is more powerful and flat shooting which I "double" the range of the .243. The .243 is pretty mild recoil wise while the 25-06 is a little more kick - but less than a .270. I bought a Savage 11 Youth rifle in .243 for when my son can hunt deer in another 2 years. It's an excellent starter rifle or for those who are more recoil sensitive.